Joni Kristin Doherty , MD, PHD
Specialties
Otolaryngology -- Head and Neck Surgery
Medical School
Oregon Health Sciences University School Of Medicine
Oregon Health Sciences University School Of Medicine
Universities
University Of California - Cum Laude
Biography
Education:
Publications:
June 4, 2008 | AAO-HNS Board Specialty Certification in Neurotology |
2004-2006 | House Clinic and House Ear Institute, Los Angeles, California, Clinical Fellow and Visiting Scientist for the Section on Signal Transduction, Department of Cell & Molecular Biology |
June 1, 2005 | Diplomate of the American Board of Otolaryngology—Head & Neck Surgery |
2000-2004 | University of Southern California, LAC+USC Medical Center, Department of Otolaryngology—Head & Neck Surgery; Resident Physician |
2002-2003 | House Ear Institute, Los Angeles, California Department of Histopathology; Visiting Scientist |
1999-2000 | LAC+USC Medical Center, Department of Surgery General Surgery Internship |
Publications:
- Richard C, Doherty JK, Fayad JN, Cordero A, Linthicum FH Jr. Identification of target proteins involved in cochlear otosclerosis. Otol Neurotol 2015;36(5):923-31. PMID 25569361
- Doherty J, Go JL, Linthicum FH Jr. Neurofibromatosis 2 invasion of the internal auditory canal wall: Clinical Significance. Otol Neurotol 2014:35(9);1662-8. NIHMS597780
- Toren A, Reichardt JK, Andalibi A Hsu NY, Doherty J, Slattery W, Mehrian-Shaw R. Novel age-dependent targets in vestibular schwannoma. Hum Genomics 2014:8;10 PMID 24980480
- Linthicum FH Jr, Doherty J, Webster P, Makarem A. The periductal channels of the endolymphatic duct, hydrodynamic implications. Otolaryngol Head Neck Surg 2014 Mar;150(3):441-7. PMID: 24376120
- Linthicum FH Jr, Doherty J, Berliner KI. Idiopathic sudden sensorineural hearing loss: Vascular or Viral? Otolaryngol Head Neck Surg 2013; 149(6):914-7. PMID 24067949
- Cassis A, Doherty JK, Daspit CP, Linthicum FH Jr. Short-term histopathology effects of gamma knife radiosurgery on a vestibular schwannoma. Otolaryngol Head Neck Surg 2013;148(6):1056-8. PMID 23426712
- Kimmel RA, Doherty J, Slattery WH III, Linthicum FH Jr. Recurrent schwannoma post-irradiation: Histological review reveals mixed schwannoma and meningioma. Otolaryngol Head Neck Surg 2013;148(5):886-8 PMID 23380761.
- Treadway JP, Doherty JK, Linthicum FH Jr. Modiolar dehiscence associated with sensorineural hearing loss. Otol Neurotol 2013 Jan;34(1):e4-5 PMID: 23235552
- Doherty JK, Linthicum FH Jr. Adipose replacing intracochlear architecture after meningioma removal. Otol Neurotol 2013;34(2):e8-9. PMID: 22972425
- Richard C, Linthicum FH Jr, Doherty JK. Incidental discovery of a temporal bone chondroblastoma on an archived histopathologic section. Otol Neurotol 2013;34(5):e38-9 PMID: 23187929
- Yi D, Kuo SZ, Zheng H, Abhold EL, Brown CM, Doherty JK, Wang-Rodriguez J, Harris JP, Ongkeko WM. Activation of PDGFR and EGFR Promotes the Acquisition of a Stem Cell-like Phenotype in Schwannomas. Otol Neurotol 2012;33(9):1640-7. PMID: 22935817
- Richard C, Doherty JK, Treadway JP, Fayad JN, Linthicum FH. Multiple otosclerotic foci: Impact on cochlear function. Otolaryngol Head Neck Surg 2012;147(2 supp):214-15. PMID 25718762
- Richard C, Fayad JN, Doherty JK, Linthicum FH, Jr. Cochlear implant round window versus cochleostomy insertion techniques: Histological findings. Otol Neurotol 2012;33(7):1181-7. PMID: 22892806
- Baik FM, Nguyen L, Doherty JK, Harris JP, Mafee MF, Nguyen QT. Comparative case series of exostoses and osteomas of the internal auditory canal. Ann Otol Rhinol Laryngol 2011;120:255-60. PMID: 21585156
- Ahmad Z, Brown CR, Ryan AF, Doherty JK. ErbB expression, activation, and inhibition with lapatinib and tyrophostin (AG825) in human vestibular schwannomas. Manuscript in press for Otol Neurotol 2011;32:841-7. PMID: 21659924
- Blair KJ, Kiang A, Wang-Rodriguez J, Yu MA, Doherty JK, Ongkeko WM. EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma. Otol Neurotol 2011;32(2):308-14. PMID: 21178801
- Altuna X, Lopez J, Yu A, Arandazi MJ, Harris JP, Wang-Rodriguez J, An Y, Dobrow R, Doherty JK, Onkeko WR. Potential Role of Imatinib Mesylate (Gleevec, STI-571) in the Treatment of Vestibular Schwannoma. Otol Neurotol 2011;32(1):163-70. PMID: 21157293
- Brown C, Ahmad Z, Ryan A, Doherty JK. Estrogen receptor expression in human vestibular schwannoma. Otol Neurotol 2011;32(1):158-62. PMID: 21099731
- Nguyen LT, Baik FM, Doherty JK, Harris JP, Nguyen QT. Exostoses and osteomas of the internal auditory canals. Laryngoscope 2010;120 Suppl 4:S215. PMID: 21225813
- Patel AK, Barkdul G, Doherty JK. Cochlear implantation in chronic suppurative otitis media. Operative Techniques in Otolaryngol 2010.
- Teufert KB, Doherty J. Endolymphatic sac shunt, labyrinthectomy, and vestibular nerve section in Meniere’s disease. Otolaryngol Clin North Am 2010; 43(5):1091-1111. PMID: 20713247
- Ahmad Z, Brown C, Patel AK, Ryan AF, Ongkeko RW, Doherty JK. Merlin knockdown in human Schwann cells: clues to vestibular schwanoma tumorigenesis. Otol Neurotol 2010;31(3):460-6. PMID: 20195187
- King J, Kinney A, Iacobellis S, Alexander TH, Harris JP, Torre P 3rd, Doherty JK, Nguyen, QT,. Laterality of exostosis in surfers due to evaporative cooling effect. Otol Neurotol 2010;31(2):345-51. PMID: 19806064
- Fisher LM, Doherty JK, Lev MH, Slattery WH III. Concordance between right and left vestibular schwannoma growth rates and hearing changes in NF2. Otol Neurotol 2009;30(6):835-41. PMID: 19704365
- Ryan AF, Mullen LM, Doherty JK. Cellular targeting for cochlear gene therapy. Adv Otorhinolaryngol 2009;66:99-115. PMID: 19494575
- Patel A, Alexander TH, Andalibi A, Ryan AF, Doherty JK. Vestibular schwannoma quantitative PCR expression of estrogen and progesterone receptors. Laryngoscope 2008;118:1458-63. PMID: 18670322
- Doherty JK, Ongkeko W, Crawley B, Andalibi A, Ryan AF. ErbB and Nrg: Potential molecular targets for vestibular schwannoma pharmacotherapy. Otol Neurotol 2008;29(1):50-57. PMID: 18199957
- Fisher LM, Doherty JK, Lev MH, Slattery WH 3rd. Distribution of nonvestibular cranial nerve schwannomas in Neurofibromatosis 2. Otol Neurotol 2007;28(8):1083-90. PMID: 18043434
- Brackmann DE, Doherty JK. Idiopathic intracranial hypertension associated with an enlarged fallopian canal and unilateral facial palsy. Otol Neurotol 2007; 28(5):715-8. PMID: 17667777
- Doherty JK, Yong M, Maceri D. Endolymphatic sac tumor: Report of three cases and discussion of management. ENT Journal 2007;86:30-5. PMID: 17315832
- Doherty JK, Brackmann DE. Malignant melanoma of the CPA: Diagnosis and Management. Otol Neurotol 2007;28:529-37. PMID: 17414177
- Doherty JK, Friedman RA. Controversies in building a management algorithm for vestibular schwannomas. Curr Opin Otolaryngology—Head & Neck Surgery 2006;14(5):305-13. PMID: 16974142
- House JW, Doherty JK, Fisher L, Masuda A, Derebery MJ. Meniere’s disease: prevalence of contralateral ear involvement. Otol Neurotol, 2006 Apr; 27(3):355-61. PMID: 16639274
- Doherty JK and Luxford WM. Management of Cochleostomy in patients with large vestibular aqueduct receiving cochlear implants. Operative Techniques in Otolaryngology, 2005;16:82-5.
- Doherty JK, Maceri DM. Osscicular discontinuity and exostoses in Proteus syndrome: a case report. Ann Otolaryngol - Head Neck Surg 2005;114:242-246. PMID: 15825577
- Doherty JK, Linthicum FH, Jr. Cochlear endosteal erosion with focal osteomyelitis induced by cochlear implantation. Otol Neurotol 2004;25(6):1029-PMID: 15547439
- Doherty JK, Linthicum FH, Jr. Spiral ligament and stria vascularis changes in cochlear otosclerosis: effect on hearing level. Otol Neurotol 2004; 25(4): 457-64. PMID: 15241221
- Doherty JK, Lum C, Doherty C. Pathology Quiz Case 2. Pemphigus Vulgaris (PV). Arch Otolaryngol - Head Neck Surg 2003, 129(2):254, 256-7. PMID: 12578463
- Doherty JK, Slattery, WH, III. Autologous fat grafting for the refractory patulous Eustachian tube. Otolaryngol - Head Neck Surg 2003, 128(1):88-91. PMID: 12574764
- Zim S, Doherty JK, Ma Y, Lee E. Pathology quiz case. Castleman’s disease (CD), unicentric, hyaline vascular type. Arch Otolaryngol Head Neck Surg 2001, 127(9): 1133-5. PMID: 11556867
- Azios, NG, Romero FJ, Denton MC, Doherty JK, Clinton GM. Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor. Oncogene 2001, 20(37):5199-5209. PMID: 11526509
- Doherty JK, Bond C, Jardim A, Adelman JP, Clinton GM. The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor. Proc Natl Acad Sci, USA 96(19): 10869-74, 1999. PMID: 10485918
- Doherty JK, Bond CT, Hua W, Adelman JP, Clinton GM. An alternative HER-2/neu transcript of 8 kb has an extended 3’UTR and displays increased stability in SKOV-3 ovarian carcinoma cells. Gynec Otol 74(3): 408-15, 1999. PMID: 10479501
- Christianson TA, Doherty JK, Lin YJ, Holmes R, Keenan EJ, Clinton GM. A truncated HER-2/neu protein with kinase activity that correlates with shedding and is elevated in metastatic breast cancer. Cancer Research 58(22): 5123-9, 1998. PMID: 9823322
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